Cialis (Drug Interactions Between Tadalafil and a-Blockers)
Another potential drug interaction exists between PDE5 inhibitors and
a blockers. In a drug-interaction study, when 20 mg of tadalafil was administered
to healthy subjects taking doxazosin (8 mg daily), an a1-adrenergic
blocker, there was a significant augmentation of the blood pressure-lowering effect of doxazosin. When 20 mg of tadalafil was administered to healthy
subjects taking 0.4-mg once-daily tamsulosin, a selective.
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