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Coumadin is used for:

Treating and preventing harmful clots that may occur in the veins (venous thrombosis), in the lungs (pulmonary embolism), with a type of abnormal heartbeat (atrial fibrillation), or following a heart valve replacement. Coumadin is also used to reduce the risk of stroke and other problems in patients who have had a heart attack. It may also be used for other conditions as determined by your doctor.

Coumadin is an anticoagulant. It works by blocking the synthesis of certain clotting factors. Without these clotting factors, blood clots are unable to form.

Do NOT use Coumadin if:

• you are allergic to any ingredient in Coumadin
• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled high blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia
• you have active serious bleeding, bleeding in the brain, certain blood vessel problems (eg, aneurysm, dissecting aorta), or inflammation or infection of the heart
• you have active ulcer or bleeding of the stomach or bowel, urinary tract, genitals, or respiratory tract
• you have recently had or will be having eye, brain, or spinal cord surgery; spinal puncture; spinal anesthesia; or any type of major surgery
• you are pregnant or may become pregnant
• you are unable to have routine blood clotting tests
• you are unable to follow your doctor’s instructions properly and do not have someone to help you take your medicine
• you are taking mifepristone, streptokinase, or urokinase

Contact your doctor or health care provider right away if any of these apply to you.

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