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Phenergan is used for:

Do NOT use Phenergan if:

• you are allergic to any ingredient in Phenergan
• you have a severe central nervous system depression or are in a coma
• you are also taking astemizole, cisapride, terfenadine, or tramadol

Before using Phenergan:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines or other substances
• if you have nervous system problems, bone marrow depression, heart problems, a blood disease, glaucoma, increased eye pressure, low blood pressure, liver problems, prostate problems, Parkinson disease, seizures, or Reye syndrome
• if you regularly consume large amounts of alcohol

• Charcoal or lithium because the effectiveness of Phenergan may be decreased
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), astemizole, cisapride, general anesthetics (eg, thiopental), methyldopa, terfenadine, or tramadol because side effects such as low blood pressure and seizures may occur
• ACE inhibitors (eg, enalapril), haloperidol, lithium, meperidine, metrizamide, monoamine oxidase (MAO) inhibitors (eg, phenelzine), naltrexone, polypeptide antibiotics (eg, actinomycin), or trazodone because the actions and side effects of these medicines may be increased
• Bromocriptine, epinephrine, levodopa, or pergolide because the effectiveness of these medicines may be decreased

How to use Phenergan:

• Phenergan may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• If you are using Phenergan for motion sickness, take a dose at least 30 to 60 minutes before you begin traveling.
• If you miss a dose of Phenergan and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to you regular dosing schedule. Do not take 2 doses at once.

Important safety information:

• Phenergan may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Phenergan. Using Phenergan alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Phenergan. Phenergan will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Neuroleptic malignant syndrome (NMS) is a potentially deadly syndrome associated with Phenergan. Symptoms include increased body heat; muscle rigidness; altered mental abilities, including lack of response to your surroundings; irregular pulse and blood pressure; increased heart rate; sweating; irregular heart rhythm. Contact your doctor at once if any of these symptoms occur.
• Phenergan may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Phenergan. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Use extreme caution when using Phenergan in the ELDERLY as they may be more sensitive to the effects of this medicine.
• Phenergan should not be used in CHILDREN under 2 years of age. Serious, and sometimes fatal, side effects (difficult or slowed breathing, drowsiness leading to coma) have occurred when Phenergan has been used in children in this age group. Phenergan should also be used with extreme caution in children 2 years of age and older. The lowest effective dose should be used in children 2 years of age and older.
• If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Phenergan during pregnancy. Phenergan is excreted in breast milk. If you are or will be breast-feeding while you are using Phenergan, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Phenergan: